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Figure 2: Comparison of the Evans blue color (μg/g tissue) in treated and nontreated groups (n = 7 in each group). The results are based on mean ± standard error of the mean. ***P < 0.001 versus Sham-OVX and Sham + OVX (a). †††P < 0.001 versus traumatic brain injury. ###P < 0.001 versus oil (b). †††P < 0.001 versus traumatic brain injury. ##P < 0.01 versus Veh. ###P < 0.001 versus Veh (c). ###P < 0.001 versus oil + Veh (d). ***P < 0.001 versus LC (e). TBI: Traumatic brain injury, oil: Estrogen vehicle, E2: Estrogen, LC: Low dose of candesartan, HC: High dose of candesartan, Veh: Candesartan vehicle, E2 + LC: Estrogen + low dose of candesartan, E2 + HC: Estrogen + high dose of candesartan, Oil + Veh: Estrogen vehicle + candesartan vehicle |
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