• Users Online: 266
  • Print this page
  • Email this page
CASE REPORT
Year : 2021  |  Volume : 10  |  Issue : 1  |  Page : 48-52

Pulmonary langerhans cell histiocytosis: Can it originate from chest trauma?


1 Medical Student/ Intern Doctor, School of Medicine, Bahcesehir University, Istanbul, Turkey
2 Department of Internal Medicine, Division of Medical Oncology, Faculty of Medicine, Bahcesehir University, Istanbul; Department of Medical Oncology, VM Medical Park Samsun Hospital, Samsun, Turkey
3 Department of Pulmonary Medicine, Faculty of Medicine, Bahcesehir University, Istanbul, Turkey

Correspondence Address:
Dr. Sevket Ozkaya
Department of Pulmonary Medicine, Faculty of Medicine, Bahcesehir University, Sahrayi Cedit Mahallesi, Batman Sk. No: 66, 34734 Kadiköy, Istanbul
Turkey
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/atr.atr_85_20

Get Permissions

Langerhans cell histiocytosis (LCH) is a rare medical condition which is defined by abnormal accumulation of a heterogeneous population of Langerhans cells that form nodules in certain tissues such as the skin, bone, and lungs. When the lungs are involved, the disease is called pulmonary LCH (PLCH). It is well established that PLCH is frequently observed in young adult smokers with equal gender distribution. Despite the clear role of smoking in PLCH pathogenesis, being a smoker rarely induces the disease, suggesting that host-related factors, inhaled antigens, or other stress-related factors may contribute to the pathogenesis. Here, we reported two cases of PLCH which both presented after chest trauma. Based on the findings from both the cases, it is concluded that the overstimulated inflammatory response in the posttraumatic lungs might be the responsible etiology resulting in the LCH if the lungs are already damaged and more sensitive due to smoking. We suggest that the differential diagnosis of PLCH should be especially considered in young adults with sudden or insidious onset of symptoms following chest trauma.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed314    
    Printed2    
    Emailed0    
    PDF Downloaded37    
    Comments [Add]    

Recommend this journal